Multiplex Smartphone Diagnostics.
نویسندگان
چکیده
Increasing computing power in smartphones allows for their transformation into point-of-care diagnostic devices. Mobile medical diagnostic applications enable utilization of the processing capabilities of smartphones through their cameras. Hardware attachments or stand-alone versions of smartphone diagnostics have the capability to revolutionize quantitative readouts. Here, we describe a protocol for quantifying commercial colorimetric diagnostic tests with a stand-alone smartphone application. This approach can be used in the multiplexed analyses of biomarker readouts.
منابع مشابه
Direct Reading of Bona Fide Barcode Assays for Diagnostics with Smartphone Apps
The desire to develop new point-of-care (POC) diagnostic tools has led to the adaptation of smartphones to tackle limitations in state-of-the-art instrumentation and centralized laboratory facilities. Today's smartphones possess the computer-like ability to image and process data using mobile apps; barcode scanners are one such type of apps. We demonstrate herein that a diagnostic assay can be ...
متن کاملSmartphone-Based Accurate Analysis of Retinal Vasculature towards Point-of-Care Diagnostics
Retinal vasculature analysis is important for the early diagnostics of various eye and systemic diseases, making it a potentially useful biomarker, especially for resource-limited regions and countries. Here we developed a smartphone-based retinal image analysis system for point-of-care diagnostics that is able to load a fundus image, segment retinal vessels, analyze individual vessel width, an...
متن کاملBIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics.
To establish the most sensitive and efficient strategy of clonality diagnostics via immunoglobulin and T-cell receptor gene rearrangement studies in suspected lymphoproliferative disorders, we evaluated 300 samples (from 218 patients) submitted consecutively for routine diagnostics. All samples were studied using the BIOMED-2 multiplex polymerase chain reaction (PCR) protocol. In 176 samples, S...
متن کاملPrinted microwells with highly stable thin-film enzyme coatings for point-of-care multiplex bioassay of blood samples.
A paper-based colorimetric biosensor suitable for point-of-care bioassay of blood samples is developed using highly stable enzyme thin-film coatings confined within inkjet printed polymeric microwells. The microwells are developed through a simple one-step inkjet printing of hydrophobic polystyrene on paper, with walls formed by the polymer that fills the gaps inside the paper body. The microwe...
متن کاملNovel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
In orthopedic patients, foreign body-associated infections, especially periprosthetic joint infections (PJIs), are a devastating complication of arthroplasty. Infection requires complex treatment, may result in long hospitalization and causes considerable costs. Multiple surgical revisions can be necessary in these patients, with a loss in function as well as in quality of life. The routine pre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Methods in molecular biology
دوره 1546 شماره
صفحات -
تاریخ انتشار 2017